Entity Details

Name IGF1R_Tyr1166
ID P08069
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
SRCIGF1RTyr1166DIYETDYyRKGGKGLphosphorylation
up-regulates activity		7493944SIGNOR-246268
IGF1RIGF1RTyr1166DIYETDYyRKGGKGLphosphorylation
up-regulates activity		7493944SIGNOR-26590
SRCIGF1RTyr1166DIYETDYyRKGGKGLphosphorylation
up-regulates		8940173SIGNOR-45130
IGF1RIGF1RTyr1166DIYETDYyRKGGKGLphosphorylation
up-regulates activity		8940173SIGNOR-246244
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
SRCphosphorylation
up-regulates
→
IGF1R
PTyr1166		phosphorylation
up-regulates
→		IGF1R7493944SIGNOR-246268
IGF1Rphosphorylation
up-regulates
→
IGF1R
PTyr1166		phosphorylation
up-regulates
→		IGF1R7493944SIGNOR-26590
SRCphosphorylation
up-regulates
→
IGF1R
PTyr1166		phosphorylation
up-regulates
→		IGF1R8940173SIGNOR-45130
IGF1Rphosphorylation
up-regulates
→
IGF1R
PTyr1166		phosphorylation
up-regulates
→		IGF1R8940173SIGNOR-246244
Regulator Mechanism/Effect Target SIGNOR-ID
SRCphosphorylation
→
up-regulates activity 		IGF1RSIGNOR-246268
IGF1Rphosphorylation
→
up-regulates activity 		IGF1RSIGNOR-26590
SRCphosphorylation
→
up-regulates 		IGF1RSIGNOR-45130
IGF1Rphosphorylation
→
up-regulates activity 		IGF1RSIGNOR-246244