Entity Details

Name PPP5C_Ser667
ID P08183
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PKCABCB1Ser667SSLIRKRsTRRSVRGdephosphorylation
up-regulates activity		24333728SIGNOR-272513
PPP5CABCB1Ser667SSLIRKRsTRRSVRGdephosphorylation
down-regulates activity		24333728SIGNOR-272506
PKAABCB1Ser667SSLIRKRsTRRSVRGdephosphorylation
up-regulates activity		24333728SIGNOR-272508
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PKCdephosphorylation
down-regulates
⊣
ABCB1
PSer667		dephosphorylation
down-regulates
⊣		ABCB124333728SIGNOR-272513
PPP5Cdephosphorylation
down-regulates
⊣
ABCB1
PSer667		dephosphorylation
up-regulates
→		ABCB124333728SIGNOR-272506
PKAdephosphorylation
down-regulates
⊣
ABCB1
PSer667		dephosphorylation
down-regulates
⊣		ABCB124333728SIGNOR-272508
Regulator Mechanism/Effect Target SIGNOR-ID
PKCdephosphorylation
→
up-regulates activity 		ABCB1SIGNOR-272513
PPP5Cdephosphorylation
→
down-regulates activity 		ABCB1SIGNOR-272506
PKAdephosphorylation
→
up-regulates activity 		ABCB1SIGNOR-272508