| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK1 | NR3C2 | Ser263 | NVGSPLSsPLSSMKS | phosphorylation down-regulates quantity by destabilization | 22798426 | SIGNOR-276105 |
| MAPK3 | NR3C2 | Ser263 | NVGSPLSsPLSSMKS | phosphorylation down-regulates quantity by destabilization | 22798426 | SIGNOR-276108 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK1 | phosphorylation up-regulates → | NR3C2 PSer263 | phosphorylation down-regulates ⊣ | NR3C2 | 22798426 | SIGNOR-276105 |
| MAPK3 | phosphorylation up-regulates → | NR3C2 PSer263 | phosphorylation down-regulates ⊣ | NR3C2 | 22798426 | SIGNOR-276108 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| MAPK1 | phosphorylation![]() down-regulates quantity by destabilization | NR3C2 | SIGNOR-276105 |
| MAPK3 | phosphorylation![]() down-regulates quantity by destabilization | NR3C2 | SIGNOR-276108 |