| Name | PTPRC |
| ID | P08575 |
| Role | substrate |
| Enzymatic Domains |
Fibronectin type-III 1 391-483 PROSITE-ProRule
Fibronectin type-III 2 484-576 PROSITE-ProRule
Tyrosine-protein phosphatase 1 653-912 PROSITE-ProRule
Tyrosine-protein phosphatase 2 944-1228 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CSNK2A1 | PTPRC | Ser1001 | SKESEHDsDESSDDD | phosphorylation up-regulates | 10066810 | SIGNOR-65281 |
| CSNK2A1 | PTPRC | Ser1005 | EHDSDESsDDDSDSE | phosphorylation up-regulates | 10066810 | SIGNOR-65273 |
| CSNK2A1 | PTPRC | Ser1009 | DESSDDDsDSEEPSK | phosphorylation up-regulates | 10066810 | SIGNOR-65277 |
| CSNK2A2 | PTPRC | Ser1009 | DESSDDDsDSEEPSK | phosphorylation up-regulates activity | 10066810 | SIGNOR-251031 |
| CSK | PTPRC | Tyr1218 | MVSTFEQyQFLYDVI | phosphorylation up-regulates | 7507203 | SIGNOR-26785 |
| CSNK2A2 | PTPRC | Ser1005 | EHDSDESsDDDSDSE | phosphorylation up-regulates activity | 10066810 | SIGNOR-251030 |
| CSNK2A1 | PTPRC | Ser1004 | SEHDSDEsSDDDSDS | phosphorylation up-regulates | 10066810 | SIGNOR-65269 |
| CSNK2A2 | PTPRC | Ser1001 | SKESEHDsDESSDDD | phosphorylation up-regulates activity | 10066810 | SIGNOR-251032 |
| CSNK2A2 | PTPRC | Ser1004 | SEHDSDEsSDDDSDS | phosphorylation up-regulates activity | 10066810 | SIGNOR-251029 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CSNK2A1 | phosphorylation up-regulates → | PTPRC PSer1001 | phosphorylation up-regulates → | PTPRC | 10066810 | SIGNOR-65281 |
| CSNK2A1 | phosphorylation up-regulates → | PTPRC PSer1005 | phosphorylation up-regulates → | PTPRC | 10066810 | SIGNOR-65273 |
| CSNK2A1 | phosphorylation up-regulates → | PTPRC PSer1009 | phosphorylation up-regulates → | PTPRC | 10066810 | SIGNOR-65277 |
| CSNK2A2 | phosphorylation up-regulates → | PTPRC PSer1009 | phosphorylation up-regulates → | PTPRC | 10066810 | SIGNOR-251031 |
| CSK | phosphorylation up-regulates → | PTPRC PTyr1218 | phosphorylation up-regulates → | PTPRC | 7507203 | SIGNOR-26785 |
| CSNK2A2 | phosphorylation up-regulates → | PTPRC PSer1005 | phosphorylation up-regulates → | PTPRC | 10066810 | SIGNOR-251030 |
| CSNK2A1 | phosphorylation up-regulates → | PTPRC PSer1004 | phosphorylation up-regulates → | PTPRC | 10066810 | SIGNOR-65269 |
| CSNK2A2 | phosphorylation up-regulates → | PTPRC PSer1001 | phosphorylation up-regulates → | PTPRC | 10066810 | SIGNOR-251032 |
| CSNK2A2 | phosphorylation up-regulates → | PTPRC PSer1004 | phosphorylation up-regulates → | PTPRC | 10066810 | SIGNOR-251029 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CSNK2A1 | phosphorylation → up-regulates | PTPRC | SIGNOR-65281 |
| CSNK2A1 | phosphorylation → up-regulates | PTPRC | SIGNOR-65273 |
| CSNK2A1 | phosphorylation → up-regulates | PTPRC | SIGNOR-65277 |
| CSNK2A2 | phosphorylation → up-regulates activity | PTPRC | SIGNOR-251031 |
| CSK | phosphorylation → up-regulates | PTPRC | SIGNOR-26785 |
| CSNK2A2 | phosphorylation → up-regulates activity | PTPRC | SIGNOR-251030 |
| CSNK2A1 | phosphorylation → up-regulates | PTPRC | SIGNOR-65269 |
| CSNK2A2 | phosphorylation → up-regulates activity | PTPRC | SIGNOR-251032 |
| CSNK2A2 | phosphorylation → up-regulates activity | PTPRC | SIGNOR-251029 |