| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PAK1 | VIM | Ser56 | SRSLYASsPGGVYAT | phosphorylation unknown | 15766329 | SIGNOR-134520 |
| CDK5 | VIM | Ser56 | SRSLYASsPGGVYAT | phosphorylation up-regulates activity | 21465480 | SIGNOR-278922 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PAK1 | phosphorylation up-regulates → | VIM PSer56 | phosphorylation down-regulates ⊣ | VIM | 15766329 | SIGNOR-134520 |
| CDK5 | phosphorylation up-regulates → | VIM PSer56 | phosphorylation up-regulates → | VIM | 21465480 | SIGNOR-278922 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PAK1 | phosphorylation → unknown | VIM | SIGNOR-134520 |
| CDK5 | phosphorylation → up-regulates activity | VIM | SIGNOR-278922 |
