| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCA | VIM | Ser26 | GTASRPSsSRSYVTT | phosphorylation down-regulates quantity by destabilization | 2500966 | SIGNOR-248882 |
| PAK2 | VIM | Ser26 | GTASRPSsSRSYVTT | phosphorylation down-regulates activity | 11895474 | SIGNOR-250237 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCA | phosphorylation up-regulates → | VIM PSer26 | phosphorylation down-regulates ⊣ | VIM | 2500966 | SIGNOR-248882 |
| PAK2 | phosphorylation up-regulates → | VIM PSer26 | phosphorylation down-regulates ⊣ | VIM | 11895474 | SIGNOR-250237 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PRKCA | phosphorylation![]() down-regulates quantity by destabilization | VIM | SIGNOR-248882 |
| PAK2 | phosphorylation → down-regulates activity | VIM | SIGNOR-250237 |