| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCA | VIM | Ser7 | sSSSYRRM | phosphorylation down-regulates quantity by destabilization | 2500966 | SIGNOR-248886 |
| PRKACA | VIM | Ser7 | sSSSYRRM | phosphorylation down-regulates activity | 2500966 | SIGNOR-250071 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCA | phosphorylation up-regulates → | VIM PSer7 | phosphorylation down-regulates ⊣ | VIM | 2500966 | SIGNOR-248886 |
| PRKACA | phosphorylation up-regulates → | VIM PSer7 | phosphorylation down-regulates ⊣ | VIM | 2500966 | SIGNOR-250071 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PRKCA | phosphorylation down-regulates quantity by destabilization | VIM | SIGNOR-248886 |
| PRKACA | phosphorylation → down-regulates activity | VIM | SIGNOR-250071 |
