| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| ROCK1 | VIM | Ser72 | SSAVRLRsSVPGVRL | phosphorylation down-regulates activity | 9565595 | SIGNOR-248998 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| ROCK1 | phosphorylation up-regulates → | VIM PSer72 | phosphorylation down-regulates ⊣ | VIM | 9565595 | SIGNOR-248998 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| ROCK1 | phosphorylation → down-regulates activity | VIM | SIGNOR-248998 |
