| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PTPN1 | ROS1 | Tyr2114 | RDIYKNDyYRKRGEG | dephosphorylation down-regulates | 17416557 | SIGNOR-154203 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PTPN1 | dephosphorylation down-regulates ⊣ | ROS1 PTyr2114 | dephosphorylation up-regulates → | ROS1 | 17416557 | SIGNOR-154203 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PTPN1 | dephosphorylation![]() down-regulates | ROS1 | SIGNOR-154203 |