Entity Details

Name PTPN6_Tyr2274
ID P08922
Role residue
View in

Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PTPN6ROS1Tyr2274KNREGLNyMVLATECdephosphorylation
down-regulates		11266449SIGNOR-105919
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PTPN6dephosphorylation
down-regulates
⊣
ROS1
PTyr2274		dephosphorylation
up-regulates
→		ROS111266449SIGNOR-105919
Regulator Mechanism/Effect Target SIGNOR-ID
PTPN6dephosphorylation
img/direct_inhibition.png
down-regulates 		ROS1SIGNOR-105919