| Name | GSTP1 |
| ID | P09211 |
| Role | substrate |
| Enzymatic Domains |
GST N-terminal 2-81
GST C-terminal 83-204 |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCZ | GSTP1 | Ser43 | VETWQEGsLKASCLY | phosphorylation up-regulates activity | 15604283 | SIGNOR-276016 |
| PRKCB | GSTP1 | Ser43 | VETWQEGsLKASCLY | phosphorylation up-regulates activity | 15604283 | SIGNOR-276022 |
| PRKCA | GSTP1 | Ser185 | SAYVGRLsARPKLKA | phosphorylation up-regulates activity | 15604283 | SIGNOR-276025 |
| PRKCE | GSTP1 | Ser43 | VETWQEGsLKASCLY | phosphorylation up-regulates activity | 15604283 | SIGNOR-276020 |
| EGFR | GSTP1 | Tyr4 | yTVVYFPV | phosphorylation up-regulates | 19254954 | SIGNOR-184383 |
| PRKCA | GSTP1 | Ser43 | VETWQEGsLKASCLY | phosphorylation up-regulates activity | 15604283 | SIGNOR-276024 |
| PRKCB | GSTP1 | Ser185 | SAYVGRLsARPKLKA | phosphorylation up-regulates activity | 15604283 | SIGNOR-276023 |
| PRKCG | GSTP1 | Ser185 | SAYVGRLsARPKLKA | phosphorylation up-regulates activity | 15604283 | SIGNOR-276019 |
| PRKCH | GSTP1 | Ser185 | SAYVGRLsARPKLKA | phosphorylation up-regulates activity | 15604283 | SIGNOR-276015 |
| PRKCH | GSTP1 | Ser43 | VETWQEGsLKASCLY | phosphorylation up-regulates activity | 15604283 | SIGNOR-276014 |
| PRKCZ | GSTP1 | Ser185 | SAYVGRLsARPKLKA | phosphorylation up-regulates activity | 15604283 | SIGNOR-276017 |
| PRKCE | GSTP1 | Ser185 | SAYVGRLsARPKLKA | phosphorylation up-regulates activity | 15604283 | SIGNOR-276021 |
| PRKCG | GSTP1 | Ser43 | VETWQEGsLKASCLY | phosphorylation up-regulates activity | 15604283 | SIGNOR-276018 |
| EGFR | GSTP1 | Tyr199 | AFLASPEyVNLPING | phosphorylation up-regulates | 19254954 | SIGNOR-184379 |
| EGFR | GSTP1 | Tyr8 | MPPYTVVyFPVRGRC | phosphorylation up-regulates | 19254954 | SIGNOR-184387 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCZ | phosphorylation up-regulates → | GSTP1 PSer43 | phosphorylation up-regulates → | GSTP1 | 15604283 | SIGNOR-276016 |
| PRKCB | phosphorylation up-regulates → | GSTP1 PSer43 | phosphorylation up-regulates → | GSTP1 | 15604283 | SIGNOR-276022 |
| PRKCA | phosphorylation up-regulates → | GSTP1 PSer185 | phosphorylation up-regulates → | GSTP1 | 15604283 | SIGNOR-276025 |
| PRKCE | phosphorylation up-regulates → | GSTP1 PSer43 | phosphorylation up-regulates → | GSTP1 | 15604283 | SIGNOR-276020 |
| EGFR | phosphorylation up-regulates → | GSTP1 PTyr4 | phosphorylation up-regulates → | GSTP1 | 19254954 | SIGNOR-184383 |
| PRKCA | phosphorylation up-regulates → | GSTP1 PSer43 | phosphorylation up-regulates → | GSTP1 | 15604283 | SIGNOR-276024 |
| PRKCB | phosphorylation up-regulates → | GSTP1 PSer185 | phosphorylation up-regulates → | GSTP1 | 15604283 | SIGNOR-276023 |
| PRKCG | phosphorylation up-regulates → | GSTP1 PSer185 | phosphorylation up-regulates → | GSTP1 | 15604283 | SIGNOR-276019 |
| PRKCH | phosphorylation up-regulates → | GSTP1 PSer185 | phosphorylation up-regulates → | GSTP1 | 15604283 | SIGNOR-276015 |
| PRKCH | phosphorylation up-regulates → | GSTP1 PSer43 | phosphorylation up-regulates → | GSTP1 | 15604283 | SIGNOR-276014 |
| PRKCZ | phosphorylation up-regulates → | GSTP1 PSer185 | phosphorylation up-regulates → | GSTP1 | 15604283 | SIGNOR-276017 |
| PRKCE | phosphorylation up-regulates → | GSTP1 PSer185 | phosphorylation up-regulates → | GSTP1 | 15604283 | SIGNOR-276021 |
| PRKCG | phosphorylation up-regulates → | GSTP1 PSer43 | phosphorylation up-regulates → | GSTP1 | 15604283 | SIGNOR-276018 |
| EGFR | phosphorylation up-regulates → | GSTP1 PTyr199 | phosphorylation up-regulates → | GSTP1 | 19254954 | SIGNOR-184379 |
| EGFR | phosphorylation up-regulates → | GSTP1 PTyr8 | phosphorylation up-regulates → | GSTP1 | 19254954 | SIGNOR-184387 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PRKCZ | phosphorylation → up-regulates activity | GSTP1 | SIGNOR-276016 |
| PRKCB | phosphorylation → up-regulates activity | GSTP1 | SIGNOR-276022 |
| PRKCA | phosphorylation → up-regulates activity | GSTP1 | SIGNOR-276025 |
| PRKCE | phosphorylation → up-regulates activity | GSTP1 | SIGNOR-276020 |
| EGFR | phosphorylation → up-regulates | GSTP1 | SIGNOR-184383 |
| PRKCA | phosphorylation → up-regulates activity | GSTP1 | SIGNOR-276024 |
| PRKCB | phosphorylation → up-regulates activity | GSTP1 | SIGNOR-276023 |
| PRKCG | phosphorylation → up-regulates activity | GSTP1 | SIGNOR-276019 |
| PRKCH | phosphorylation → up-regulates activity | GSTP1 | SIGNOR-276015 |
| PRKCH | phosphorylation → up-regulates activity | GSTP1 | SIGNOR-276014 |
| PRKCZ | phosphorylation → up-regulates activity | GSTP1 | SIGNOR-276017 |
| PRKCE | phosphorylation → up-regulates activity | GSTP1 | SIGNOR-276021 |
| PRKCG | phosphorylation → up-regulates activity | GSTP1 | SIGNOR-276018 |
| EGFR | phosphorylation → up-regulates | GSTP1 | SIGNOR-184379 |
| EGFR | phosphorylation → up-regulates | GSTP1 | SIGNOR-184387 |