| Name | HNRNPA1 |
| ID | P09651 |
| Role | substrate |
| Enzymatic Domains |
RRM 1 14-97 PROSITE-ProRule
RRM 2 105-184 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| AKT | HNRNPA1 | Ser199 | SQRGRSGsGNFGGGR | phosphorylation down-regulates | 18562319 | SIGNOR-179059 |
| PRKCA | HNRNPA1 | Ser95 | RAVSREDsQRPGAHL | phosphorylation down-regulates | 7727389 | SIGNOR-32291 |
| RPS6KB2 | HNRNPA1 | Ser6 | sPKEPEQL | phosphorylation up-regulates activity | 25324306 | SIGNOR-279569 |
| AKT1 | HNRNPA1 | Ser199 | SQRGRSGsGNFGGGR | phosphorylation down-regulates | 18562319 | SIGNOR-252519 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| AKT | phosphorylation up-regulates → | HNRNPA1 PSer199 | phosphorylation down-regulates ⊣ | HNRNPA1 | 18562319 | SIGNOR-179059 |
| PRKCA | phosphorylation up-regulates → | HNRNPA1 PSer95 | phosphorylation down-regulates ⊣ | HNRNPA1 | 7727389 | SIGNOR-32291 |
| RPS6KB2 | phosphorylation up-regulates → | HNRNPA1 PSer6 | phosphorylation up-regulates → | HNRNPA1 | 25324306 | SIGNOR-279569 |
| AKT1 | phosphorylation up-regulates → | HNRNPA1 PSer199 | phosphorylation down-regulates ⊣ | HNRNPA1 | 18562319 | SIGNOR-252519 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| AKT | phosphorylation down-regulates | HNRNPA1 | SIGNOR-179059 |
| PRKCA | phosphorylation down-regulates | HNRNPA1 | SIGNOR-32291 |
| RPS6KB2 | phosphorylation → up-regulates activity | HNRNPA1 | SIGNOR-279569 |
| AKT1 | phosphorylation down-regulates | HNRNPA1 | SIGNOR-252519 |