| Name | FGR |
| ID | P09769 |
| Role | substrate |
| Enzymatic Domains |
SH3 77-138 PROSITE-ProRule
SH2 144-241 PROSITE-ProRule
Protein kinase 263-516 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| FGR | FGR | Tyr412 | RLIKDDEyNPCQGSK | phosphorylation up-regulates activity | 8612628 | SIGNOR-251143 |
| CSK | FGR | Tyr523 | FTSAEPQyQPGDQT | phosphorylation down-regulates activity | 7515063 | SIGNOR-250779 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| FGR | phosphorylation up-regulates → | FGR PTyr412 | phosphorylation up-regulates → | FGR | 8612628 | SIGNOR-251143 |
| CSK | phosphorylation up-regulates → | FGR PTyr523 | phosphorylation down-regulates ⊣ | FGR | 7515063 | SIGNOR-250779 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| FGR | phosphorylation → up-regulates activity | FGR | SIGNOR-251143 |
| CSK | phosphorylation → down-regulates activity | FGR | SIGNOR-250779 |