Entity Details

Name PRKACA_Ser785
ID P09874
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CDK5PARP1Ser785LRGGSDDsSKDPIDVphosphorylation
down-regulates activity		21922195SIGNOR-276358
PRKACAPARP1Ser785LRGGSDDsSKDPIDVphosphorylation
up-regulates activity		25069723SIGNOR-276653
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CDK5phosphorylation
up-regulates
→
PARP1
PSer785		phosphorylation
down-regulates
⊣		PARP121922195SIGNOR-276358
PRKACAphosphorylation
up-regulates
→
PARP1
PSer785		phosphorylation
up-regulates
→		PARP125069723SIGNOR-276653
Regulator Mechanism/Effect Target SIGNOR-ID
CDK5phosphorylation
→
down-regulates activity 		PARP1SIGNOR-276358
PRKACAphosphorylation
→
up-regulates activity 		PARP1SIGNOR-276653