Entity Details

Name MAPKAPK2_Ser272
ID P09917
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
ERK1/2ALOX5Ser272CSLERQLsLEQEVQQphosphorylation
up-regulates activity		12670876SIGNOR-264443
CAMK2AALOX5Ser272CSLERQLsLEQEVQQphosphorylation
up-regulates activity		18978352SIGNOR-264408
MAPKAPK2ALOX5Ser272CSLERQLsLEQEVQQphosphorylation
up-regulates activity		11844797SIGNOR-250143
MAPK1ALOX5Ser272CSLERQLsLEQEVQQphosphorylation
up-regulates activity		12670876SIGNOR-264439
MAPK3ALOX5Ser272CSLERQLsLEQEVQQphosphorylation
up-regulates activity		12670876SIGNOR-264441
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
ERK1/2phosphorylation
up-regulates
→
ALOX5
PSer272		phosphorylation
up-regulates
→		ALOX512670876SIGNOR-264443
CAMK2Aphosphorylation
up-regulates
→
ALOX5
PSer272		phosphorylation
up-regulates
→		ALOX518978352SIGNOR-264408
MAPKAPK2phosphorylation
up-regulates
→
ALOX5
PSer272		phosphorylation
up-regulates
→		ALOX511844797SIGNOR-250143
MAPK1phosphorylation
up-regulates
→
ALOX5
PSer272		phosphorylation
up-regulates
→		ALOX512670876SIGNOR-264439
MAPK3phosphorylation
up-regulates
→
ALOX5
PSer272		phosphorylation
up-regulates
→		ALOX512670876SIGNOR-264441
Regulator Mechanism/Effect Target SIGNOR-ID
ERK1/2phosphorylation
→
up-regulates activity 		ALOX5SIGNOR-264443
CAMK2Aphosphorylation
→
up-regulates activity 		ALOX5SIGNOR-264408
MAPKAPK2phosphorylation
→
up-regulates activity 		ALOX5SIGNOR-250143
MAPK1phosphorylation
→
up-regulates activity 		ALOX5SIGNOR-264439
MAPK3phosphorylation
→
up-regulates activity 		ALOX5SIGNOR-264441