| Name | CALM2 |
| ID | P0DP24 |
| Role | substrate |
| Enzymatic Domains |
EF-hand 1 8-43 PROSITE-ProRule
EF-hand 2 44-79 PROSITE-ProRule
EF-hand 3 81-116 PROSITE-ProRule
EF-hand 4 117-149 PROSITE-ProRule |
View in  |
|
| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| EGFR | CALM2 | Tyr100 | FDKDGNGyISAAELR | phosphorylation down-regulates | 3415247 | SIGNOR-266319 |
| INSR | CALM2 | Tyr100 | FDKDGNGyISAAELR | phosphorylation down-regulates | 3415247 | SIGNOR-266320 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| EGFR | phosphorylation up-regulates → | CALM2 PTyr100 | phosphorylation down-regulates ⊣ | CALM2 | 3415247 | SIGNOR-266319 |
| INSR | phosphorylation up-regulates → | CALM2 PTyr100 | phosphorylation down-regulates ⊣ | CALM2 | 3415247 | SIGNOR-266320 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| EGFR | phosphorylation down-regulates | CALM2 | SIGNOR-266319 |
| INSR | phosphorylation down-regulates | CALM2 | SIGNOR-266320 |