| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| INSR | CALM2 | Tyr100 | FDKDGNGyISAAELR | phosphorylation down-regulates | 3415247 | SIGNOR-266320 |
| EGFR | CALM2 | Tyr100 | FDKDGNGyISAAELR | phosphorylation down-regulates | 3415247 | SIGNOR-266319 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| INSR | phosphorylation up-regulates → | CALM2 PTyr100 | phosphorylation down-regulates ⊣ | CALM2 | 3415247 | SIGNOR-266320 |
| EGFR | phosphorylation up-regulates → | CALM2 PTyr100 | phosphorylation down-regulates ⊣ | CALM2 | 3415247 | SIGNOR-266319 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| INSR | phosphorylation![]() down-regulates | CALM2 | SIGNOR-266320 |
| EGFR | phosphorylation![]() down-regulates | CALM2 | SIGNOR-266319 |