Entity Details

Name CDK9_Ser83
ID P10275
Role residue
View in

Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PP2Ca_R1A_Bd ARSer83QQQQQETsPRQQQQQdephosphorylation
down-regulates activity		27858941SIGNOR-254759
PTENARSer83QQQQQETsPRQQQQQdephosphorylation
up-regulates activity		24480624SIGNOR-277077
CDK1ARSer83QQQQQETsPRQQQQQphosphorylation
up-regulates		21799006SIGNOR-175692
CDK9ARSer83QQQQQETsPRQQQQQphosphorylation
up-regulates activity		28062857SIGNOR-279456
CDK5ARSer83QQQQQETsPRQQQQQphosphorylation
up-regulates		21799006SIGNOR-175696
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PP2Ca_R1A_Bd dephosphorylation
down-regulates
⊣
AR
PSer83		dephosphorylation
up-regulates
→		AR27858941SIGNOR-254759
PTENdephosphorylation
down-regulates
⊣
AR
PSer83		dephosphorylation
down-regulates
⊣		AR24480624SIGNOR-277077
CDK1phosphorylation
up-regulates
→
AR
PSer83		phosphorylation
up-regulates
→		AR21799006SIGNOR-175692
CDK9phosphorylation
up-regulates
→
AR
PSer83		phosphorylation
up-regulates
→		AR28062857SIGNOR-279456
CDK5phosphorylation
up-regulates
→
AR
PSer83		phosphorylation
up-regulates
→		AR21799006SIGNOR-175696
Regulator Mechanism/Effect Target SIGNOR-ID
PP2Ca_R1A_Bd dephosphorylation
→
down-regulates activity 		ARSIGNOR-254759
PTENdephosphorylation
→
up-regulates activity 		ARSIGNOR-277077
CDK1phosphorylation
→
up-regulates 		ARSIGNOR-175692
CDK9phosphorylation
→
up-regulates activity 		ARSIGNOR-279456
CDK5phosphorylation
→
up-regulates 		ARSIGNOR-175696