| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CyclinD3/CDK11A | AR | Ser310 | TEDTAEYsPFKGGYT | phosphorylation down-regulates quantity by destabilization | 17698582 | SIGNOR-273125 |
| CyclinD3/CDK11B | AR | Ser310 | TEDTAEYsPFKGGYT | phosphorylation down-regulates quantity by destabilization | 17698582 | SIGNOR-273130 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CyclinD3/CDK11A | phosphorylation up-regulates → | AR PSer310 | phosphorylation down-regulates ⊣ | AR | 17698582 | SIGNOR-273125 |
| CyclinD3/CDK11B | phosphorylation up-regulates → | AR PSer310 | phosphorylation down-regulates ⊣ | AR | 17698582 | SIGNOR-273130 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CyclinD3/CDK11A | phosphorylation![]() down-regulates quantity by destabilization | AR | SIGNOR-273125 |
| CyclinD3/CDK11B | phosphorylation![]() down-regulates quantity by destabilization | AR | SIGNOR-273130 |