| Name | RARA |
| ID | P10276 |
| Role | substrate |
| Enzymatic Domains |
NR LBD 183-417 PROSITE-ProRule |
View in ![]() |
|
| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| TFIIH | RARA | Ser77 | EIVPSPPsPPPLPRI | phosphorylation unknown | 11955452 | SIGNOR-269332 |
| PRKACA | RARA | Ser369 | YVRKRRPsRPHMFPK | phosphorylation down-regulates activity | 20215566 | SIGNOR-276282 |
| PRKACA | RARA | Ser219 | NSSEQRVsLDIDLWD | phosphorylation down-regulates activity | 20215566 | SIGNOR-276281 |
| CDK7 | RARA | Ser77 | EIVPSPPsPPPLPRI | phosphorylation up-regulates | 9230306 | SIGNOR-49693 |
| AKT1 | RARA | Ser96 | FVCQDKSsGYHYGVS | phosphorylation down-regulates | 16417524 | SIGNOR-252489 |
| CDK7 | RARA | Ser77 | EIVPSPPsPPPLPRI | phosphorylation unknown | 11955452 | SIGNOR-116582 |
| AKT | RARA | Ser96 | FVCQDKSsGYHYGVS | phosphorylation down-regulates | 16417524 | SIGNOR-143721 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| TFIIH | phosphorylation up-regulates → | RARA PSer77 | phosphorylation down-regulates ⊣ | RARA | 11955452 | SIGNOR-269332 |
| PRKACA | phosphorylation up-regulates → | RARA PSer369 | phosphorylation down-regulates ⊣ | RARA | 20215566 | SIGNOR-276282 |
| PRKACA | phosphorylation up-regulates → | RARA PSer219 | phosphorylation down-regulates ⊣ | RARA | 20215566 | SIGNOR-276281 |
| CDK7 | phosphorylation up-regulates → | RARA PSer77 | phosphorylation up-regulates → | RARA | 9230306 | SIGNOR-49693 |
| AKT1 | phosphorylation up-regulates → | RARA PSer96 | phosphorylation down-regulates ⊣ | RARA | 16417524 | SIGNOR-252489 |
| CDK7 | phosphorylation up-regulates → | RARA PSer77 | phosphorylation down-regulates ⊣ | RARA | 11955452 | SIGNOR-116582 |
| AKT | phosphorylation up-regulates → | RARA PSer96 | phosphorylation down-regulates ⊣ | RARA | 16417524 | SIGNOR-143721 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| TFIIH | phosphorylation → unknown | RARA | SIGNOR-269332 |
| PRKACA | phosphorylation → down-regulates activity | RARA | SIGNOR-276282 |
| PRKACA | phosphorylation → down-regulates activity | RARA | SIGNOR-276281 |
| CDK7 | phosphorylation → up-regulates | RARA | SIGNOR-49693 |
| AKT1 | phosphorylation![]() down-regulates | RARA | SIGNOR-252489 |
| CDK7 | phosphorylation → unknown | RARA | SIGNOR-116582 |
| AKT | phosphorylation![]() down-regulates | RARA | SIGNOR-143721 |