Entity Details

Name RARA
ID P10276
Role substrate
Enzymatic Domains
NR LBD 183-417
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
TFIIHRARASer77EIVPSPPsPPPLPRIphosphorylation
unknown
11955452SIGNOR-269332
PRKACARARASer369YVRKRRPsRPHMFPKphosphorylation
down-regulates activity
20215566SIGNOR-276282
PRKACARARASer219NSSEQRVsLDIDLWDphosphorylation
down-regulates activity
20215566SIGNOR-276281
CDK7RARASer77EIVPSPPsPPPLPRIphosphorylation
up-regulates
9230306SIGNOR-49693
AKT1RARASer96FVCQDKSsGYHYGVSphosphorylation
down-regulates
16417524SIGNOR-252489
CDK7RARASer77EIVPSPPsPPPLPRIphosphorylation
unknown
11955452SIGNOR-116582
AKTRARASer96FVCQDKSsGYHYGVSphosphorylation
down-regulates
16417524SIGNOR-143721
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
TFIIHphosphorylation
up-regulates
RARA
PSer77
phosphorylation
down-regulates
RARA11955452SIGNOR-269332
PRKACAphosphorylation
up-regulates
RARA
PSer369
phosphorylation
down-regulates
RARA20215566SIGNOR-276282
PRKACAphosphorylation
up-regulates
RARA
PSer219
phosphorylation
down-regulates
RARA20215566SIGNOR-276281
CDK7phosphorylation
up-regulates
RARA
PSer77
phosphorylation
up-regulates
RARA9230306SIGNOR-49693
AKT1phosphorylation
up-regulates
RARA
PSer96
phosphorylation
down-regulates
RARA16417524SIGNOR-252489
CDK7phosphorylation
up-regulates
RARA
PSer77
phosphorylation
down-regulates
RARA11955452SIGNOR-116582
AKTphosphorylation
up-regulates
RARA
PSer96
phosphorylation
down-regulates
RARA16417524SIGNOR-143721
Regulator Mechanism/Effect Target SIGNOR-ID
TFIIHphosphorylation

unknown
RARASIGNOR-269332
PRKACAphosphorylation

down-regulates activity
RARASIGNOR-276282
PRKACAphosphorylation

down-regulates activity
RARASIGNOR-276281
CDK7phosphorylation

up-regulates
RARASIGNOR-49693
AKT1phosphorylation
img/direct_inhibition.png
down-regulates
RARASIGNOR-252489
CDK7phosphorylation

unknown
RARASIGNOR-116582
AKTphosphorylation
img/direct_inhibition.png
down-regulates
RARASIGNOR-143721