| Name | ARAF |
| ID | P10398 |
| Role | substrate |
| Enzymatic Domains |
RBD 19-91 PROSITE-ProRule
Protein kinase 310-570 PROSITE-ProRule |
View in  |
|
| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| SRC | ARAF | Tyr302 | GYRDSGYyWEVPPSE | phosphorylation up-regulates activity | 9020159 | SIGNOR-236459 |
| SRC | ARAF | Tyr301 | LGYRDSGyYWEVPPS | phosphorylation up-regulates | 9020159 | SIGNOR-236037 |
| PAK1 | ARAF | Ser299 | KNLGYRDsGYYWEVP | phosphorylation up-regulates | 15710605 | SIGNOR-236342 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| SRC | phosphorylation up-regulates → | ARAF PTyr302 | phosphorylation up-regulates → | ARAF | 9020159 | SIGNOR-236459 |
| SRC | phosphorylation up-regulates → | ARAF PTyr301 | phosphorylation up-regulates → | ARAF | 9020159 | SIGNOR-236037 |
| PAK1 | phosphorylation up-regulates → | ARAF PSer299 | phosphorylation up-regulates → | ARAF | 15710605 | SIGNOR-236342 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| SRC | phosphorylation → up-regulates activity | ARAF | SIGNOR-236459 |
| SRC | phosphorylation → up-regulates | ARAF | SIGNOR-236037 |
| PAK1 | phosphorylation → up-regulates | ARAF | SIGNOR-236342 |