Entity Details

Name MAPT
ID P10636-2
Role substrate
Enzymatic Domains
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PRKAA1MAPTSer267RVQSKIGsLDNITHVphosphorylation
down-regulates activity		10090741SIGNOR-275438
PRKCBMAPTSer324RHLSNVSsTGSIDMVphosphorylation
down-regulates activity		10090741SIGNOR-275442
MARK2MAPTSer324RHLSNVSsTGSIDMVphosphorylation
down-regulates activity		10090741SIGNOR-275437
PRKCGMAPTSer324RHLSNVSsTGSIDMVphosphorylation
down-regulates activity		10090741SIGNOR-275445
MARK2MAPTSer267RVQSKIGsLDNITHVphosphorylation
down-regulates activity		10090741SIGNOR-275435
PRKCIMAPTSer324RHLSNVSsTGSIDMVphosphorylation
down-regulates activity		10090741SIGNOR-275446
MAPK3MAPTSer267RVQSKIGsLDNITHVphosphorylation
down-regulates activity		10090741SIGNOR-275434
PRKCZMAPTSer324RHLSNVSsTGSIDMVphosphorylation
down-regulates activity		10090741SIGNOR-275447
PRKCBMAPTSer324RHLSNVSsTGSIDMVphosphorylation
down-regulates activity		10090741SIGNOR-275443
PRKCEMAPTSer324RHLSNVSsTGSIDMVphosphorylation
down-regulates activity		10090741SIGNOR-275444
PRKCAMAPTSer324RHLSNVSsTGSIDMVphosphorylation
down-regulates activity		10090741SIGNOR-275441
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PRKAA1phosphorylation
up-regulates
→
MAPT
PSer267		phosphorylation
down-regulates
⊣		MAPT10090741SIGNOR-275438
PRKCBphosphorylation
up-regulates
→
MAPT
PSer324		phosphorylation
down-regulates
⊣		MAPT10090741SIGNOR-275442
MARK2phosphorylation
up-regulates
→
MAPT
PSer324		phosphorylation
down-regulates
⊣		MAPT10090741SIGNOR-275437
PRKCGphosphorylation
up-regulates
→
MAPT
PSer324		phosphorylation
down-regulates
⊣		MAPT10090741SIGNOR-275445
MARK2phosphorylation
up-regulates
→
MAPT
PSer267		phosphorylation
down-regulates
⊣		MAPT10090741SIGNOR-275435
PRKCIphosphorylation
up-regulates
→
MAPT
PSer324		phosphorylation
down-regulates
⊣		MAPT10090741SIGNOR-275446
MAPK3phosphorylation
up-regulates
→
MAPT
PSer267		phosphorylation
down-regulates
⊣		MAPT10090741SIGNOR-275434
PRKCZphosphorylation
up-regulates
→
MAPT
PSer324		phosphorylation
down-regulates
⊣		MAPT10090741SIGNOR-275447
PRKCBphosphorylation
up-regulates
→
MAPT
PSer324		phosphorylation
down-regulates
⊣		MAPT10090741SIGNOR-275443
PRKCEphosphorylation
up-regulates
→
MAPT
PSer324		phosphorylation
down-regulates
⊣		MAPT10090741SIGNOR-275444
PRKCAphosphorylation
up-regulates
→
MAPT
PSer324		phosphorylation
down-regulates
⊣		MAPT10090741SIGNOR-275441
Regulator Mechanism/Effect Target SIGNOR-ID
PRKAA1phosphorylation
→
down-regulates activity 		MAPTSIGNOR-275438
PRKCBphosphorylation
→
down-regulates activity 		MAPTSIGNOR-275442
MARK2phosphorylation
→
down-regulates activity 		MAPTSIGNOR-275437
PRKCGphosphorylation
→
down-regulates activity 		MAPTSIGNOR-275445
MARK2phosphorylation
→
down-regulates activity 		MAPTSIGNOR-275435
PRKCIphosphorylation
→
down-regulates activity 		MAPTSIGNOR-275446
MAPK3phosphorylation
→
down-regulates activity 		MAPTSIGNOR-275434
PRKCZphosphorylation
→
down-regulates activity 		MAPTSIGNOR-275447
PRKCBphosphorylation
→
down-regulates activity 		MAPTSIGNOR-275443
PRKCEphosphorylation
→
down-regulates activity 		MAPTSIGNOR-275444
PRKCAphosphorylation
→
down-regulates activity 		MAPTSIGNOR-275441