Entity Details

Name MAPT
ID P10636-4
Role substrate
Enzymatic Domains
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
AMPKMAPTSer352PRHLSNVsSTGSIDMphosphorylation
down-regulates activity		21204788SIGNOR-273929
MARK4MAPTSer353RHLSNVSsTGSIDMVphosphorylation
down-regulates activity		21204788SIGNOR-273934
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
AMPKphosphorylation
up-regulates
→
MAPT
PSer352		phosphorylation
down-regulates
⊣		MAPT21204788SIGNOR-273929
MARK4phosphorylation
up-regulates
→
MAPT
PSer353		phosphorylation
down-regulates
⊣		MAPT21204788SIGNOR-273934
Regulator Mechanism/Effect Target SIGNOR-ID
AMPKphosphorylation
→
down-regulates activity 		MAPTSIGNOR-273929
MARK4phosphorylation
→
down-regulates activity 		MAPTSIGNOR-273934