Entity Details

Name CAMK2A_Ser552
ID P10636
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CDK5MAPTSer552VVRTPPKsPSSAKSRphosphorylation
down-regulates activity		12387894SIGNOR-249319
CAMK2AMAPTSer552VVRTPPKsPSSAKSRphosphorylation
down-regulates activity		10090741SIGNOR-249316
CDK5/CDK5R1MAPTSer552VVRTPPKsPSSAKSRphosphorylation
down-regulates activity		12387894SIGNOR-251590
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CDK5phosphorylation
up-regulates
→
MAPT
PSer552		phosphorylation
down-regulates
⊣		MAPT12387894SIGNOR-249319
CAMK2Aphosphorylation
up-regulates
→
MAPT
PSer552		phosphorylation
down-regulates
⊣		MAPT10090741SIGNOR-249316
CDK5/CDK5R1phosphorylation
up-regulates
→
MAPT
PSer552		phosphorylation
down-regulates
⊣		MAPT12387894SIGNOR-251590
Regulator Mechanism/Effect Target SIGNOR-ID
CDK5phosphorylation
→
down-regulates activity 		MAPTSIGNOR-249319
CAMK2Aphosphorylation
→
down-regulates activity 		MAPTSIGNOR-249316
CDK5/CDK5R1phosphorylation
→
down-regulates activity 		MAPTSIGNOR-251590