Entity Details

Name MAPK12_Ser637
ID P10636
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PKN1MAPTSer637VDLSKVTsKCGSLGNphosphorylation
down-regulates		11104762SIGNOR-84958
MAPK12MAPTSer637VDLSKVTsKCGSLGNphosphorylation
down-regulates activity		9199504SIGNOR-250085
MARK1MAPTSer637VDLSKVTsKCGSLGNphosphorylation
down-regulates activity		10090741SIGNOR-250173
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PKN1phosphorylation
up-regulates
→
MAPT
PSer637		phosphorylation
down-regulates
⊣		MAPT11104762SIGNOR-84958
MAPK12phosphorylation
up-regulates
→
MAPT
PSer637		phosphorylation
down-regulates
⊣		MAPT9199504SIGNOR-250085
MARK1phosphorylation
up-regulates
→
MAPT
PSer637		phosphorylation
down-regulates
⊣		MAPT10090741SIGNOR-250173
Regulator Mechanism/Effect Target SIGNOR-ID
PKN1phosphorylation
img/direct_inhibition.png
down-regulates 		MAPTSIGNOR-84958
MAPK12phosphorylation
→
down-regulates activity 		MAPTSIGNOR-250085
MARK1phosphorylation
→
down-regulates activity 		MAPTSIGNOR-250173