Entity Details

Name MARK1_Ser641
ID P10636
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
MARK1MAPTSer641KVTSKCGsLGNIHHKphosphorylation
down-regulates		21215781SIGNOR-171054
MARK1MAPTSer641KVTSKCGsLGNIHHKphosphorylation
down-regulates activity		10090741SIGNOR-250174
GSK3AMAPTSer641KVTSKCGsLGNIHHKphosphorylation
down-regulates activity		7706316SIGNOR-249342
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
MARK1phosphorylation
up-regulates
→
MAPT
PSer641		phosphorylation
down-regulates
⊣		MAPT21215781SIGNOR-171054
MARK1phosphorylation
up-regulates
→
MAPT
PSer641		phosphorylation
down-regulates
⊣		MAPT10090741SIGNOR-250174
GSK3Aphosphorylation
up-regulates
→
MAPT
PSer641		phosphorylation
down-regulates
⊣		MAPT7706316SIGNOR-249342
Regulator Mechanism/Effect Target SIGNOR-ID
MARK1phosphorylation
img/direct_inhibition.png
down-regulates 		MAPTSIGNOR-171054
MARK1phosphorylation
→
down-regulates activity 		MAPTSIGNOR-250174
GSK3Aphosphorylation
→
down-regulates activity 		MAPTSIGNOR-249342