Entity Details

Name PRKACA_Ser531
ID P10636
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CDK5MAPTSer531GSRSRTPsLPTPPTRphosphorylation
down-regulates activity		12387894SIGNOR-249318
CDK5/CDK5R1MAPTSer531GSRSRTPsLPTPPTRphosphorylation
down-regulates activity		12387894SIGNOR-251589
GSK3BMAPTSer531GSRSRTPsLPTPPTRphosphorylation
down-regulates activity		12387894SIGNOR-249344
PRKACAMAPTSer531GSRSRTPsLPTPPTRphosphorylation
down-regulates activity		9614189SIGNOR-250006
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CDK5phosphorylation
up-regulates
→
MAPT
PSer531		phosphorylation
down-regulates
⊣		MAPT12387894SIGNOR-249318
CDK5/CDK5R1phosphorylation
up-regulates
→
MAPT
PSer531		phosphorylation
down-regulates
⊣		MAPT12387894SIGNOR-251589
GSK3Bphosphorylation
up-regulates
→
MAPT
PSer531		phosphorylation
down-regulates
⊣		MAPT12387894SIGNOR-249344
PRKACAphosphorylation
up-regulates
→
MAPT
PSer531		phosphorylation
down-regulates
⊣		MAPT9614189SIGNOR-250006
Regulator Mechanism/Effect Target SIGNOR-ID
CDK5phosphorylation
→
down-regulates activity 		MAPTSIGNOR-249318
CDK5/CDK5R1phosphorylation
→
down-regulates activity 		MAPTSIGNOR-251589
GSK3Bphosphorylation
→
down-regulates activity 		MAPTSIGNOR-249344
PRKACAphosphorylation
→
down-regulates activity 		MAPTSIGNOR-250006