Entity Details

Name PRKACA_Ser673
ID P10636
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
MARK1MAPTSer673RVQSKIGsLDNITHVphosphorylation
down-regulates		21215781SIGNOR-171058
MARK1MAPTSer673RVQSKIGsLDNITHVphosphorylation
down-regulates activity		10090741SIGNOR-250175
PRKACAMAPTSer673RVQSKIGsLDNITHVphosphorylation
down-regulates activity		12435421SIGNOR-250007
NUAK1MAPTSer673RVQSKIGsLDNITHVphosphorylation
up-regulates quantity		27720485SIGNOR-279306
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
MARK1phosphorylation
up-regulates
→
MAPT
PSer673		phosphorylation
down-regulates
⊣		MAPT21215781SIGNOR-171058
MARK1phosphorylation
up-regulates
→
MAPT
PSer673		phosphorylation
down-regulates
⊣		MAPT10090741SIGNOR-250175
PRKACAphosphorylation
up-regulates
→
MAPT
PSer673		phosphorylation
down-regulates
⊣		MAPT12435421SIGNOR-250007
NUAK1phosphorylation
up-regulates
→
MAPT
PSer673		phosphorylation
up-regulates
→		MAPT27720485SIGNOR-279306
Regulator Mechanism/Effect Target SIGNOR-ID
MARK1phosphorylation
img/direct_inhibition.png
down-regulates 		MAPTSIGNOR-171058
MARK1phosphorylation
→
down-regulates activity 		MAPTSIGNOR-250175
PRKACAphosphorylation
→
down-regulates activity 		MAPTSIGNOR-250007
NUAK1phosphorylation
→
up-regulates quantity 		MAPTSIGNOR-279306