| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CyclinY/CDK16 | PRKAR1A | Ser83 | DSREDEIsPPPPNPV | phosphorylation up-regulates activity | 25605337 | SIGNOR-273014 |
| PRKG1 | PRKAR1A | Ser101 | RRRRGAIsAEVYTEE | phosphorylation up-regulates activity | 29378851 | SIGNOR-277383 |
| CDK16 | PRKAR1A | Ser83 | DSREDEIsPPPPNPV | phosphorylation up-regulates activity | 25605337 | SIGNOR-273018 |
| CyclinE/CDK2 | PRKAR1A | Ser83 | DSREDEIsPPPPNPV | phosphorylation up-regulates | 16582606 | SIGNOR-216729 |
| CDK2 | PRKAR1A | Ser83 | DSREDEIsPPPPNPV | phosphorylation up-regulates | 16582606 | SIGNOR-145577 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CyclinY/CDK16 | phosphorylation up-regulates → | PRKAR1A PSer83 | phosphorylation up-regulates → | PRKAR1A | 25605337 | SIGNOR-273014 |
| PRKG1 | phosphorylation up-regulates → | PRKAR1A PSer101 | phosphorylation up-regulates → | PRKAR1A | 29378851 | SIGNOR-277383 |
| CDK16 | phosphorylation up-regulates → | PRKAR1A PSer83 | phosphorylation up-regulates → | PRKAR1A | 25605337 | SIGNOR-273018 |
| CyclinE/CDK2 | phosphorylation up-regulates → | PRKAR1A PSer83 | phosphorylation up-regulates → | PRKAR1A | 16582606 | SIGNOR-216729 |
| CDK2 | phosphorylation up-regulates → | PRKAR1A PSer83 | phosphorylation up-regulates → | PRKAR1A | 16582606 | SIGNOR-145577 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CyclinY/CDK16 | phosphorylation → up-regulates activity | PRKAR1A | SIGNOR-273014 |
| PRKG1 | phosphorylation → up-regulates activity | PRKAR1A | SIGNOR-277383 |
| CDK16 | phosphorylation → up-regulates activity | PRKAR1A | SIGNOR-273018 |
| CyclinE/CDK2 | phosphorylation → up-regulates | PRKAR1A | SIGNOR-216729 |
| CDK2 | phosphorylation → up-regulates | PRKAR1A | SIGNOR-145577 |
