| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCA | KIT | Ser746 | RRSVRIGsYIERDVT | phosphorylation down-regulates activity | 7539802 | SIGNOR-248899 |
| PRKCA | KIT | Ser746 | RRSVRIGsYIERDVT | phosphorylation down-regulates | 7539802 | SIGNOR-28605 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCA | phosphorylation up-regulates → | KIT PSer746 | phosphorylation down-regulates ⊣ | KIT | 7539802 | SIGNOR-248899 |
| PRKCA | phosphorylation up-regulates → | KIT PSer746 | phosphorylation down-regulates ⊣ | KIT | 7539802 | SIGNOR-28605 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PRKCA | phosphorylation → down-regulates activity | KIT | SIGNOR-248899 |
| PRKCA | phosphorylation down-regulates | KIT | SIGNOR-28605 |
