Entity Details

Name ITK_Tyr218
ID P10747
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
ITKCD28Tyr218PPRDFAAyRSphosphorylation
up-regulates activity		8992971SIGNOR-251337
ITKCD28Tyr218PPRDFAAyRSphosphorylation
up-regulates		8992971SIGNOR-45520
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
ITKphosphorylation
up-regulates
→
CD28
PTyr218		phosphorylation
up-regulates
→		CD288992971SIGNOR-251337
ITKphosphorylation
up-regulates
→
CD28
PTyr218		phosphorylation
up-regulates
→		CD288992971SIGNOR-45520
Regulator Mechanism/Effect Target SIGNOR-ID
ITKphosphorylation
→
up-regulates activity 		CD28SIGNOR-251337
ITKphosphorylation
→
up-regulates 		CD28SIGNOR-45520