Entity Details

Name PTPN1_Tyr487
ID P10912
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PTPN1GHRTyr487SLSNIDFyAQVSDITdephosphorylation
down-regulates activity		12907755SIGNOR-248419
PTPN2GHRTyr487SLSNIDFyAQVSDITdephosphorylation
down-regulates activity		12907755SIGNOR-248392
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PTPN1dephosphorylation
down-regulates
⊣
GHR
PTyr487		dephosphorylation
up-regulates
→		GHR12907755SIGNOR-248419
PTPN2dephosphorylation
down-regulates
⊣
GHR
PTyr487		dephosphorylation
up-regulates
→		GHR12907755SIGNOR-248392
Regulator Mechanism/Effect Target SIGNOR-ID
PTPN1dephosphorylation
→
down-regulates activity 		GHRSIGNOR-248419
PTPN2dephosphorylation
→
down-regulates activity 		GHRSIGNOR-248392