Entity Details

Name PTPN1_Tyr534
ID P10912
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PTPN3GHRTyr534NFLMDNAyFCEADAKdephosphorylation
down-regulates activity		12907755SIGNOR-248459
PTPN1GHRTyr534NFLMDNAyFCEADAKdephosphorylation
down-regulates activity		12907755SIGNOR-248420
PTPN2GHRTyr534NFLMDNAyFCEADAKdephosphorylation
down-regulates activity		12907755SIGNOR-248393
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PTPN3dephosphorylation
down-regulates
⊣
GHR
PTyr534		dephosphorylation
up-regulates
→		GHR12907755SIGNOR-248459
PTPN1dephosphorylation
down-regulates
⊣
GHR
PTyr534		dephosphorylation
up-regulates
→		GHR12907755SIGNOR-248420
PTPN2dephosphorylation
down-regulates
⊣
GHR
PTyr534		dephosphorylation
up-regulates
→		GHR12907755SIGNOR-248393
Regulator Mechanism/Effect Target SIGNOR-ID
PTPN3dephosphorylation
→
down-regulates activity 		GHRSIGNOR-248459
PTPN1dephosphorylation
→
down-regulates activity 		GHRSIGNOR-248420
PTPN2dephosphorylation
→
down-regulates activity 		GHRSIGNOR-248393