Entity Details

Name IRF1
ID P10914
Role substrate
Enzymatic Domains
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
IKBKEIRF1Ser215DLYNFQVsPMPSTSEphosphorylation
down-regulates activity		24396068SIGNOR-276480
IKBKEIRF1Ser219FQVSPMPsTSEATTDphosphorylation
down-regulates activity		24396068SIGNOR-276478
IKBKEIRF1Ser221VSPMPSTsEATTDEDphosphorylation
down-regulates activity		24396068SIGNOR-276479
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
IKBKEphosphorylation
up-regulates
→
IRF1
PSer215		phosphorylation
down-regulates
⊣		IRF124396068SIGNOR-276480
IKBKEphosphorylation
up-regulates
→
IRF1
PSer219		phosphorylation
down-regulates
⊣		IRF124396068SIGNOR-276478
IKBKEphosphorylation
up-regulates
→
IRF1
PSer221		phosphorylation
down-regulates
⊣		IRF124396068SIGNOR-276479
Regulator Mechanism/Effect Target SIGNOR-ID
IKBKEphosphorylation
→
down-regulates activity 		IRF1SIGNOR-276480
IKBKEphosphorylation
→
down-regulates activity 		IRF1SIGNOR-276478
IKBKEphosphorylation
→
down-regulates activity 		IRF1SIGNOR-276479