Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
MARK1	MAP2	Ser1540 View in OncoXplorer	KSPEKRSsLPRPSSI	phosphorylation down-regulates activity	8631898	SIGNOR-250163
MARK1	MAP2	Ser1795 View in OncoXplorer	VASPRRLsNVSSSGS	phosphorylation down-regulates activity	8631898	SIGNOR-250166
PRKACA	MAP2	Ser1710	HVTSKCGsLKNIRHR	phosphorylation down-regulates activity	11029056	SIGNOR-250002
MARK1	MAP2	Ser1679 View in OncoXplorer	NVKSKIGsTDNIKYQ	phosphorylation down-regulates activity	8631898	SIGNOR-250164
PRKACA	MAP2	Ser1679 View in OncoXplorer	NVKSKIGsTDNIKYQ	phosphorylation down-regulates activity	11029056	SIGNOR-250001
MARK1	MAP2	Ser1802 View in OncoXplorer	SNVSSSGsINLLESP	phosphorylation down-regulates activity	8631898	SIGNOR-250168
MARK1	MAP2	Ser1799 View in OncoXplorer	RRLSNVSsSGSINLL	phosphorylation down-regulates activity	8631898	SIGNOR-250167
KNDC1	MAP2	–		phosphorylation up-regulates activity	17984326	SIGNOR-278950
PRKACA	MAP2	Ser1742 View in OncoXplorer	KAQAKVGsLDNAHHV	phosphorylation down-regulates activity	11029056	SIGNOR-250003
PRKACA	MAP2	Ser1782 View in OncoXplorer	GAEIITQsPGRSSVA	phosphorylation up-regulates	11029056	SIGNOR-83100
MARK1	MAP2	Ser1710	HVTSKCGsLKNIRHR	phosphorylation down-regulates activity	8631898	SIGNOR-250165

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
MARK1	phosphorylation up-regulates →	MAP2 PSer1540	phosphorylation down-regulates ⊣	MAP2	8631898	SIGNOR-250163
MARK1	phosphorylation up-regulates →	MAP2 PSer1795	phosphorylation down-regulates ⊣	MAP2	8631898	SIGNOR-250166
PRKACA	phosphorylation up-regulates →	MAP2 PSer1710	phosphorylation down-regulates ⊣	MAP2	11029056	SIGNOR-250002
MARK1	phosphorylation up-regulates →	MAP2 PSer1679	phosphorylation down-regulates ⊣	MAP2	8631898	SIGNOR-250164
PRKACA	phosphorylation up-regulates →	MAP2 PSer1679	phosphorylation down-regulates ⊣	MAP2	11029056	SIGNOR-250001
MARK1	phosphorylation up-regulates →	MAP2 PSer1802	phosphorylation down-regulates ⊣	MAP2	8631898	SIGNOR-250168
MARK1	phosphorylation up-regulates →	MAP2 PSer1799	phosphorylation down-regulates ⊣	MAP2	8631898	SIGNOR-250167
PRKACA	phosphorylation up-regulates →	MAP2 PSer1742	phosphorylation down-regulates ⊣	MAP2	11029056	SIGNOR-250003
PRKACA	phosphorylation up-regulates →	MAP2 PSer1782	phosphorylation up-regulates →	MAP2	11029056	SIGNOR-83100
MARK1	phosphorylation up-regulates →	MAP2 PSer1710	phosphorylation down-regulates ⊣	MAP2	8631898	SIGNOR-250165

Regulator	Mechanism/Effect	Target	SIGNOR-ID
MARK1	phosphorylation → down-regulates activity	MAP2	SIGNOR-250163
MARK1	phosphorylation → down-regulates activity	MAP2	SIGNOR-250166
PRKACA	phosphorylation → down-regulates activity	MAP2	SIGNOR-250002
MARK1	phosphorylation → down-regulates activity	MAP2	SIGNOR-250164
PRKACA	phosphorylation → down-regulates activity	MAP2	SIGNOR-250001
MARK1	phosphorylation → down-regulates activity	MAP2	SIGNOR-250168
MARK1	phosphorylation → down-regulates activity	MAP2	SIGNOR-250167
KNDC1	phosphorylation → up-regulates activity	MAP2	SIGNOR-278950
PRKACA	phosphorylation → down-regulates activity	MAP2	SIGNOR-250003
PRKACA	phosphorylation → up-regulates	MAP2	SIGNOR-83100
MARK1	phosphorylation → down-regulates activity	MAP2	SIGNOR-250165