Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
EGFR	EPB41	Tyr660	RLDGENIyIRHSNLM	phosphorylation down-regulates	1647028	SIGNOR-20452

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
EGFR	phosphorylation up-regulates →	EPB41 PTyr660	phosphorylation down-regulates ⊣	EPB41	1647028	SIGNOR-20452

Regulator	Mechanism/Effect	Target	SIGNOR-ID
EGFR	phosphorylation down-regulates	EPB41	SIGNOR-20452