| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PPP2CB | RALA | Ser194 | NGKKKRKsLAKRIRE | dephosphorylation down-regulates | 17540176 | SIGNOR-155353 |
| AURKA | RALA | Ser194 | NGKKKRKsLAKRIRE | phosphorylation up-regulates activity | 21822277 | SIGNOR-278351 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PPP2CB | dephosphorylation down-regulates ⊣ | RALA PSer194 | dephosphorylation up-regulates → | RALA | 17540176 | SIGNOR-155353 |
| AURKA | phosphorylation up-regulates → | RALA PSer194 | phosphorylation up-regulates → | RALA | 21822277 | SIGNOR-278351 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PPP2CB | dephosphorylation down-regulates | RALA | SIGNOR-155353 |
| AURKA | phosphorylation → up-regulates activity | RALA | SIGNOR-278351 |
