Entity Details

Name BCR-ABL_Tyr177
ID P11274
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
FESBCRTyr177ADAEKPFyVNVEFHHphosphorylation
down-regulates activity		8955135SIGNOR-251136
BCR-ABLBCRTyr177ADAEKPFyVNVEFHHphosphorylation
down-regulates activity		8622703SIGNOR-40611
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
FESphosphorylation
up-regulates
→
BCR
PTyr177		phosphorylation
down-regulates
⊣		BCR8955135SIGNOR-251136
BCR-ABLphosphorylation
up-regulates
→
BCR
PTyr177		phosphorylation
down-regulates
⊣		BCR8622703SIGNOR-40611
Regulator Mechanism/Effect Target SIGNOR-ID
FESphosphorylation
→
down-regulates activity 		BCRSIGNOR-251136
BCR-ABLphosphorylation
→
down-regulates activity 		BCRSIGNOR-40611