Entity Details

Name BCR-ABL_Tyr283
ID P11274
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
BCR-ABLBCRTyr283YQPYQSIyVGGMMEGphosphorylation
down-regulates		8622703SIGNOR-40615
FESBCRTyr283YQPYQSIyVGGMMEGphosphorylation
down-regulates		8955135SIGNOR-45343
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
BCR-ABLphosphorylation
up-regulates
→
BCR
PTyr283		phosphorylation
down-regulates
⊣		BCR8622703SIGNOR-40615
FESphosphorylation
up-regulates
→
BCR
PTyr283		phosphorylation
down-regulates
⊣		BCR8955135SIGNOR-45343
Regulator Mechanism/Effect Target SIGNOR-ID
BCR-ABLphosphorylation
img/direct_inhibition.png
down-regulates 		BCRSIGNOR-40615
FESphosphorylation
img/direct_inhibition.png
down-regulates 		BCRSIGNOR-45343