| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| BCR-ABL | BCR | Tyr360 | VSPSPTTyRMFRDKS | phosphorylation down-regulates activity | 8622703 | SIGNOR-262530 |
| BCR-ABL | BCR | Tyr360 | YSPRSFEdCGGGYTP | phosphorylation down-regulates activity | 9467953 | SIGNOR-260828 |
| BCR-ABL | BCR | Tyr360 | VSPSPTTyRMFRDKS | phosphorylation down-regulates | 8622703 | SIGNOR-40619 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| BCR-ABL | phosphorylation up-regulates → | BCR PTyr360 | phosphorylation down-regulates ⊣ | BCR | 8622703 | SIGNOR-262530 |
| BCR-ABL | phosphorylation up-regulates → | BCR PTyr360 | phosphorylation down-regulates ⊣ | BCR | 9467953 | SIGNOR-260828 |
| BCR-ABL | phosphorylation up-regulates → | BCR PTyr360 | phosphorylation down-regulates ⊣ | BCR | 8622703 | SIGNOR-40619 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| BCR-ABL | phosphorylation → down-regulates activity | BCR | SIGNOR-262530 |
| BCR-ABL | phosphorylation → down-regulates activity | BCR | SIGNOR-260828 |
| BCR-ABL | phosphorylation down-regulates | BCR | SIGNOR-40619 |
