| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| FES | BCR | Tyr246 | SCGVDGDyEDAELNP | phosphorylation down-regulates activity | 8955135 | SIGNOR-251137 |
| FES | BCR | Tyr246 | SCGVDGDyEDAELNP | phosphorylation down-regulates | 8955135 | SIGNOR-45330 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| FES | phosphorylation up-regulates → | BCR PTyr246 | phosphorylation down-regulates ⊣ | BCR | 8955135 | SIGNOR-251137 |
| FES | phosphorylation up-regulates → | BCR PTyr246 | phosphorylation down-regulates ⊣ | BCR | 8955135 | SIGNOR-45330 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| FES | phosphorylation → down-regulates activity | BCR | SIGNOR-251137 |
| FES | phosphorylation down-regulates | BCR | SIGNOR-45330 |
