| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| BCR-ABL | BCR | Tyr283 | YQPYQSIyVGGMMEG | phosphorylation down-regulates | 8622703 | SIGNOR-40615 |
| FES | BCR | Tyr283 | YQPYQSIyVGGMMEG | phosphorylation down-regulates | 8955135 | SIGNOR-45343 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| BCR-ABL | phosphorylation up-regulates → | BCR PTyr283 | phosphorylation down-regulates ⊣ | BCR | 8622703 | SIGNOR-40615 |
| FES | phosphorylation up-regulates → | BCR PTyr283 | phosphorylation down-regulates ⊣ | BCR | 8955135 | SIGNOR-45343 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| BCR-ABL | phosphorylation down-regulates | BCR | SIGNOR-40615 |
| FES | phosphorylation down-regulates | BCR | SIGNOR-45343 |
