Entity Details

Name PRKDC_Ser10
ID P11387
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PRKDCTOP1Ser10GDHLHNDsQIEADFRphosphorylation
down-regulates quantity by destabilization		28415827SIGNOR-277352
CSNK2A1TOP1Ser10GDHLHNDsQIEADFRphosphorylation
up-regulates activity		18408216SIGNOR-276155
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PRKDCphosphorylation
up-regulates
→
TOP1
PSer10		phosphorylation
down-regulates
⊣		TOP128415827SIGNOR-277352
CSNK2A1phosphorylation
up-regulates
→
TOP1
PSer10		phosphorylation
up-regulates
→		TOP118408216SIGNOR-276155
Regulator Mechanism/Effect Target SIGNOR-ID
PRKDCphosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		TOP1SIGNOR-277352
CSNK2A1phosphorylation
→
up-regulates activity 		TOP1SIGNOR-276155