Entity Details

Name TOP1_Ser112
ID P11387
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CDK1TOP1Ser112
View in OncoXplorer
EKENGFSsPPQIKDEphosphorylation
up-regulates activity		18408216SIGNOR-276156
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CDK1phosphorylation
up-regulates
→
TOP1
PSer112		phosphorylation
up-regulates
→		TOP118408216SIGNOR-276156
Regulator Mechanism/Effect Target SIGNOR-ID
CDK1phosphorylation
→
up-regulates activity 		TOP1SIGNOR-276156