Entity Details

Name TOP1_Ser21
ID P11387
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PRKCATOP1Ser21ADFRLNDsHKHKDKHphosphorylation
up-regulates activity		18408216SIGNOR-276154
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PRKCAphosphorylation
up-regulates
→
TOP1
PSer21		phosphorylation
up-regulates
→		TOP118408216SIGNOR-276154
Regulator Mechanism/Effect Target SIGNOR-ID
PRKCAphosphorylation
→
up-regulates activity 		TOP1SIGNOR-276154