Entity Details

Name TOP1_Ser394
ID P11387
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CDK1TOP1Ser394
View in OncoXplorer
SKDAKVPsPPPGHKWphosphorylation
up-regulates activity		18408216SIGNOR-276157
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CDK1phosphorylation
up-regulates
→
TOP1
PSer394		phosphorylation
up-regulates
→		TOP118408216SIGNOR-276157
Regulator Mechanism/Effect Target SIGNOR-ID
CDK1phosphorylation
→
up-regulates activity 		TOP1SIGNOR-276157