Entity Details

Name TOP1_Tyr268
ID P11387
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
ABL1TOP1Tyr268AKMLDHEyTTKEIFRphosphorylation
up-regulates activity		15448168SIGNOR-260775
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
ABL1phosphorylation
up-regulates
→
TOP1
PTyr268		phosphorylation
up-regulates
→		TOP115448168SIGNOR-260775
Regulator Mechanism/Effect Target SIGNOR-ID
ABL1phosphorylation
→
up-regulates activity 		TOP1SIGNOR-260775