| Name | IGF2R |
| ID | P11717 |
| Role | substrate |
| Enzymatic Domains |
MRH 1 47-163 PROSITE-ProRule
MRH 2 172-320 PROSITE-ProRule
MRH 3 326-468 PROSITE-ProRule
MRH 4 473-619 PROSITE-ProRule
MRH 5 625-762 PROSITE-ProRule
MRH 6 765-924 PROSITE-ProRule
MRH 7 932-1079 PROSITE-ProRule
MRH 8 1082-1219 PROSITE-ProRule
MRH 9 1225-1363 PROSITE-ProRule
MRH 10 1367-1508 PROSITE-ProRule
MRH 11 1514-1648 PROSITE-ProRule
MRH 12 1650-1797 PROSITE-ProRule
Fibronectin type-II 1802-1989 PROSITE-ProRule
MRH 14 1992-2127 PROSITE-ProRule
MRH 15 2135-2280 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKACA | IGF2R | Ser2347 | TTCCRRSsNVSYKYS | phosphorylation unknown | 8318012 | SIGNOR-37839 |
| CSNK2A1 | IGF2R | Ser2484 | LVSFHDDsDEDLLHI | phosphorylation unknown | 8318012 | SIGNOR-37835 |
| CSNK2A1 | IGF2R | Ser2409 | LHGDDQDsEDEVLTI | phosphorylation unknown | 8318012 | SIGNOR-37831 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKACA | phosphorylation up-regulates → | IGF2R PSer2347 | phosphorylation down-regulates ⊣ | IGF2R | 8318012 | SIGNOR-37839 |
| CSNK2A1 | phosphorylation up-regulates → | IGF2R PSer2484 | phosphorylation down-regulates ⊣ | IGF2R | 8318012 | SIGNOR-37835 |
| CSNK2A1 | phosphorylation up-regulates → | IGF2R PSer2409 | phosphorylation down-regulates ⊣ | IGF2R | 8318012 | SIGNOR-37831 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PRKACA | phosphorylation → unknown | IGF2R | SIGNOR-37839 |
| CSNK2A1 | phosphorylation → unknown | IGF2R | SIGNOR-37835 |
| CSNK2A1 | phosphorylation → unknown | IGF2R | SIGNOR-37831 |