| Name | SRF |
| ID | P11831 |
| Role | substrate |
| Enzymatic Domains |
MADS-box 141-201 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPKAPK2 | SRF | Ser103 | RGLKRSLsEMEIGMV | phosphorylation unknown | 10318869 | SIGNOR-67448 |
| CSNK2A1 | SRF | Ser77 | PTAGALYsGSEGDSE | phosphorylation up-regulates activity | 2046671 | SIGNOR-250955 |
| PRKDC | SRF | Ser435 | LTVLNAFsQAPSTMQ | phosphorylation up-regulates activity | 8407951 | SIGNOR-248921 |
| PRKACA | SRF | Thr159 | DNKLRRYtTFSKRKT | phosphorylation up-regulates | 12809504 | SIGNOR-188177 |
| CAMK2A | SRF | Ser103 | RGLKRSLsEMEIGMV | phosphorylation up-regulates activity | 10753652 | SIGNOR-250638 |
| PRKG1 | SRF | Thr159 | DNKLRRYtTFSKRKT | phosphorylation up-regulates | 12809504 | SIGNOR-188185 |
| PRKCA | SRF | Thr159 | DNKLRRYtTFSKRKT | phosphorylation up-regulates | 12809504 | SIGNOR-188181 |
| PRKCD | SRF | Thr160 | NKLRRYTtFSKRKTG | phosphorylation down-regulates activity | 15282327 | SIGNOR-279347 |
| MAPKAPK2 | SRF | – | phosphorylation up-regulates | 20626350 | SIGNOR-166640 | |
| DMPK | SRF | Thr159 | DNKLRRYtTFSKRKT | phosphorylation up-regulates | 12809504 | SIGNOR-236982 |
| CSNK2A1 | SRF | Ser85 | GSEGDSEsGEEEELG | phosphorylation up-regulates activity | 2046671 | SIGNOR-250957 |
| PRKCA | SRF | Ser162 | LRRYTTFsKRKTGIM | phosphorylation down-regulates | 16537394 | SIGNOR-234461 |
| PRKDC | SRF | Ser446 | STMQVSHsQVQEPGG | phosphorylation up-regulates activity | 8407951 | SIGNOR-248922 |
| CAMK2A | SRF | Thr160 | NKLRRYTtFSKRKTG | phosphorylation up-regulates activity | 10753652 | SIGNOR-250639 |
| CSNK2A1 | SRF | Ser83 | YSGSEGDsESGEEEE | phosphorylation up-regulates activity | 2046671 | SIGNOR-250958 |
| CSNK2A1 | SRF | Ser79 | AGALYSGsEGDSESG | phosphorylation up-regulates activity | 2046671 | SIGNOR-250956 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPKAPK2 | phosphorylation up-regulates → | SRF PSer103 | phosphorylation down-regulates ⊣ | SRF | 10318869 | SIGNOR-67448 |
| CSNK2A1 | phosphorylation up-regulates → | SRF PSer77 | phosphorylation up-regulates → | SRF | 2046671 | SIGNOR-250955 |
| PRKDC | phosphorylation up-regulates → | SRF PSer435 | phosphorylation up-regulates → | SRF | 8407951 | SIGNOR-248921 |
| PRKACA | phosphorylation up-regulates → | SRF PThr159 | phosphorylation up-regulates → | SRF | 12809504 | SIGNOR-188177 |
| CAMK2A | phosphorylation up-regulates → | SRF PSer103 | phosphorylation up-regulates → | SRF | 10753652 | SIGNOR-250638 |
| PRKG1 | phosphorylation up-regulates → | SRF PThr159 | phosphorylation up-regulates → | SRF | 12809504 | SIGNOR-188185 |
| PRKCA | phosphorylation up-regulates → | SRF PThr159 | phosphorylation up-regulates → | SRF | 12809504 | SIGNOR-188181 |
| PRKCD | phosphorylation up-regulates → | SRF PThr160 | phosphorylation down-regulates ⊣ | SRF | 15282327 | SIGNOR-279347 |
| DMPK | phosphorylation up-regulates → | SRF PThr159 | phosphorylation up-regulates → | SRF | 12809504 | SIGNOR-236982 |
| CSNK2A1 | phosphorylation up-regulates → | SRF PSer85 | phosphorylation up-regulates → | SRF | 2046671 | SIGNOR-250957 |
| PRKCA | phosphorylation up-regulates → | SRF PSer162 | phosphorylation down-regulates ⊣ | SRF | 16537394 | SIGNOR-234461 |
| PRKDC | phosphorylation up-regulates → | SRF PSer446 | phosphorylation up-regulates → | SRF | 8407951 | SIGNOR-248922 |
| CAMK2A | phosphorylation up-regulates → | SRF PThr160 | phosphorylation up-regulates → | SRF | 10753652 | SIGNOR-250639 |
| CSNK2A1 | phosphorylation up-regulates → | SRF PSer83 | phosphorylation up-regulates → | SRF | 2046671 | SIGNOR-250958 |
| CSNK2A1 | phosphorylation up-regulates → | SRF PSer79 | phosphorylation up-regulates → | SRF | 2046671 | SIGNOR-250956 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| MAPKAPK2 | phosphorylation → unknown | SRF | SIGNOR-67448 |
| CSNK2A1 | phosphorylation → up-regulates activity | SRF | SIGNOR-250955 |
| PRKDC | phosphorylation → up-regulates activity | SRF | SIGNOR-248921 |
| PRKACA | phosphorylation → up-regulates | SRF | SIGNOR-188177 |
| CAMK2A | phosphorylation → up-regulates activity | SRF | SIGNOR-250638 |
| PRKG1 | phosphorylation → up-regulates | SRF | SIGNOR-188185 |
| PRKCA | phosphorylation → up-regulates | SRF | SIGNOR-188181 |
| PRKCD | phosphorylation → down-regulates activity | SRF | SIGNOR-279347 |
| MAPKAPK2 | phosphorylation → up-regulates | SRF | SIGNOR-166640 |
| DMPK | phosphorylation → up-regulates | SRF | SIGNOR-236982 |
| CSNK2A1 | phosphorylation → up-regulates activity | SRF | SIGNOR-250957 |
| PRKCA | phosphorylation down-regulates | SRF | SIGNOR-234461 |
| PRKDC | phosphorylation → up-regulates activity | SRF | SIGNOR-248922 |
| CAMK2A | phosphorylation → up-regulates activity | SRF | SIGNOR-250639 |
| CSNK2A1 | phosphorylation → up-regulates activity | SRF | SIGNOR-250958 |
| CSNK2A1 | phosphorylation → up-regulates activity | SRF | SIGNOR-250956 |