| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| LATS2 | PRPS2 | Thr285 | EDKMKHCtKIQVIDI | phosphorylation down-regulates quantity by destabilization | 34465890 | SIGNOR-276507 |
| LATS1 | PRPS2 | Thr285 | EDKMKHCtKIQVIDI | phosphorylation down-regulates quantity by destabilization | 34465890 | SIGNOR-276506 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| LATS2 | phosphorylation up-regulates → | PRPS2 PThr285 | phosphorylation down-regulates ⊣ | PRPS2 | 34465890 | SIGNOR-276507 |
| LATS1 | phosphorylation up-regulates → | PRPS2 PThr285 | phosphorylation down-regulates ⊣ | PRPS2 | 34465890 | SIGNOR-276506 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| LATS2 | phosphorylation![]() down-regulates quantity by destabilization | PRPS2 | SIGNOR-276507 |
| LATS1 | phosphorylation![]() down-regulates quantity by destabilization | PRPS2 | SIGNOR-276506 |